Quantifying Evidence for Candidate Gene Polymorphisms: Bayesian Analysis Combining Sequence-Specific and Quantitative Trait Loci Colocation Information
نویسندگان
چکیده
منابع مشابه
Quantifying evidence for candidate gene polymorphisms: Bayesian analysis combining sequence-specific and quantitative trait loci colocation information.
We calculate posterior probabilities for candidate genes as a function of genomic location. Posterior probabilities for quantitative trait loci (QTL) presence in a small interval are calculated using a Bayesian model-selection approach based on the Bayesian information criterion (BIC) and used to combine QTL colocation information with sequence-specific evidence, e.g., from differential express...
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ژورنال
عنوان ژورنال: Genetics
سال: 2007
ISSN: 1943-2631
DOI: 10.1534/genetics.106.069955